TY  - JOUR
T1  - Bacterial Cellulose Matrix and Acellular Dermal Matrix Seeded with Fibroblasts Grown in Platelet-Rich Plasma Supplemented Medium, Compared to Free Gingival Grafts: A Randomized Animal Study
A1  - Ekaterini Loutrouki
JF  - Annals of Orthodontics and Periodontics Specialty
JO  - Ann Orthod Periodontics Spec
SN  - 3062-3405
Y1  - 2024
VL  - 4
IS  - 1
DO  - 10.51847/WY68rTFTak
SP  - 229
EP  - 239
N2  - Mucogingival defects (MGDs), such as dental root recessions, decreased vestibular depth, and absence of keratinized tissues, are commonly seen in dental clinics. MGDs may result in functional, aesthetic, and hygienic concerns. In these situations, autogenous soft tissue grafts are considered the gold-standard treatment. This study compares the healing process of free gingival grafts (FGGs) to bacterial cellulose matrix (BCM) and human acellular dermal matrix (ADM) seeded with fibroblasts from culture supplemented with platelet-rich plasma in a rat model. Surgical defects were made in rats, which received the following treatments in a randomized manner: group I, negative control (defect creation only); group II, positive control (FGG); group III, BCM; group IV, BCM + fibroblasts; group V, ADM; and group VI, ADM + fibroblasts. Clinical, histological, and immunological analyses were performed 15 days after grafting. Clinical examinations recorded epithelium regularity and the presence of ulcers, erythema, and/or edema. The histological analysis revealed the degree of reepithelization, width, regularity, and presence of keratin. The Fisher exact statistical test was applied to the results (P
UR  - https://aopsj.com/article/bacterial-cellulose-matrix-and-acellular-dermal-matrix-seeded-with-fibroblasts-grown-in-platelet-ric-lzrtu2sa4pyrzpg
ER  -